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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NFS1
All Species:
37.27
Human Site:
T422
Identified Species:
63.08
UniProt:
Q9Y697
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y697
NP_066923.3
457
50196
T422
T
E
E
E
V
D
Y
T
V
E
K
C
I
Q
H
Chimpanzee
Pan troglodytes
XP_001165456
457
50158
T422
T
E
E
E
V
D
Y
T
V
E
K
C
I
Q
H
Rhesus Macaque
Macaca mulatta
XP_001097983
457
50117
T422
T
E
E
E
V
D
Y
T
V
E
K
C
I
Q
H
Dog
Lupus familis
XP_534405
457
50277
T422
T
E
E
E
V
D
Y
T
V
E
K
C
I
H
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1J3
451
49983
T416
T
E
E
E
V
D
Y
T
A
E
K
C
I
H
H
Rat
Rattus norvegicus
Q99P39
451
49994
T416
T
E
E
E
V
D
Y
T
V
Q
K
C
I
H
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026018
445
49074
T410
T
E
E
E
I
D
Y
T
V
Q
K
C
I
Q
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038458
451
50210
T416
T
E
E
E
V
D
Y
T
A
E
K
C
I
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKD3
462
51056
T427
T
V
E
E
V
D
Y
T
A
D
K
C
I
K
H
Honey Bee
Apis mellifera
XP_393524
423
46979
A389
I
E
E
I
D
Y
T
A
E
N
T
I
R
H
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789397
779
88565
T744
T
E
E
E
V
D
Y
T
A
E
K
C
V
H
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001148578
451
49661
A416
T
D
E
E
V
D
R
A
I
E
L
T
V
H
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O49543
453
50277
A418
T
K
E
E
I
D
K
A
V
E
L
T
V
K
Q
Baker's Yeast
Sacchar. cerevisiae
P25374
497
54449
V462
T
E
E
E
V
D
Y
V
V
K
A
V
S
D
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.6
94
N.A.
90.8
91.4
N.A.
N.A.
80.9
N.A.
74.4
N.A.
69
68.7
N.A.
46.6
Protein Similarity:
100
99.3
99.3
96
N.A.
94.3
95.4
N.A.
N.A.
87.3
N.A.
84.6
N.A.
81.5
80.9
N.A.
52.3
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
N.A.
86.6
N.A.
80
N.A.
73.3
13.3
N.A.
73.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
100
N.A.
80
N.A.
86.6
13.3
N.A.
80
Percent
Protein Identity:
N.A.
66.9
N.A.
60.6
57.7
N.A.
Protein Similarity:
N.A.
80.3
N.A.
74.6
71
N.A.
P-Site Identity:
N.A.
40
N.A.
40
53.3
N.A.
P-Site Similarity:
N.A.
60
N.A.
66.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
22
29
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
72
0
0
0
% C
% Asp:
0
8
0
0
8
93
0
0
0
8
0
0
0
8
0
% D
% Glu:
0
79
100
93
0
0
0
0
8
65
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
58
% H
% Ile:
8
0
0
8
15
0
0
0
8
0
0
8
65
0
0
% I
% Lys:
0
8
0
0
0
0
8
0
0
8
72
0
0
15
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
15
0
0
0
29
22
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% S
% Thr:
93
0
0
0
0
0
8
72
0
0
8
15
0
0
0
% T
% Val:
0
8
0
0
79
0
0
8
58
0
0
8
22
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
79
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _